Types of genetic testing for patients undergoing to IVF:
Preimplantation genetic testing (PGT) is used to detect chromosomal abnormalities in embryos created through IVF before pregnancy. There are two different types of genetic testing methods which are commonly used at fertility hospitals and IVF clinics–- Preimplantation genetic screening (PGS),
- Preimplantation genetic diagnosis (PGD).
Is genetic testing for IVF worth it?
PGT testing is done before embryo transfer but after 5 to 6 days of embryo development processes. Is genetic testing worth it in IVF? Yes, it is recommended but not required and may vary depending on individual circumstances and preferences. Here are the benefits and drawbacks of preimplantation genetic testing to help you decide whether it is worth it or not.Pros of Preimplantation Genetic Testing (PGT):
- Risk Reduction: Identifies embryos with genetic abnormalities, reducing the risk of passing on inherited disorders to the child.
- Increased Pregnancy Success: Helps select embryos with higher chances of successful implantation, leading to increased pregnancy rates.
- Reduced Miscarriage Risk: Lower likelihood of miscarriage, specifically for women over 35, as a result of selecting embryos less prone to chromosomal abnormalities.
- Time and Cost Efficiency: This can potentially reduce the number of IVF cycles needed by selecting healthier embryos, saving time and costs.
Cons of Preimplantation Genetic Testing (PGT):
- False Positives/Negatives: This is not infallible, and there is a small chance of false positives or negatives, leading to a potential misinterpretation of genetic information. However, the accuracy is highlighted at 98% in a survey.
- Invasive Procedure: Involves the removal of cells from the embryo; in such a process, embryos may not survive the biopsy procedure.
- Limited Scope: It may not detect all genetic abnormalities, and it primarily focuses on the specific conditions targeted during testing.