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ADVANCED MATERNAL AGE AND IN VITRO FERTILIZATION

In medical world, the GERIATRIC PREGNANCY  is an old term that was generally  used to  denotes a pregnancy in a woman over the age of 35. Nowadays , medical practitioners use the term ADVANCED MATERNAL AGE instead. Advanced maternal age is connected with a decrease in both ovarian reserve and oocyte competence. Despite the fact that all pregnancies come with certain amount of risk, regardless of any reproductive age. But the possibilities of complications are much higher in elderly gravida.

 

POSSIBLE FACTORS THAT INFLUENCE CHILD- BEARING AGE

(A) REDUCED FECUNDITY-Women’s age plays a pivotal role in natural healthy conception. A women peaks fertility during their 20s and first half of 30s and after that it starts to decline , resulting in increased risk of female infertility. Age related decrease in the number of oocytes , as well as disturbed neuroendocrine function of ovary and lesions in uterus, contribute to reduced fertility.

(B) OVARIAN AGEING – The biological state of the ovum remains the keystone in normal reproduction. Decreasing number of ovarian follicles with age is also accompanied by reduction of their quality, including mainly congenital anomalies of the nucleus such as decondensation of the chromosomes , abnormalities related with spindle apparatus and dispersed chromatin. This eventually results in failed reproduction due to abnormal gametogenesis and fertilization process, early development of the embryo and  abnormal implantation.

(C) LIFESTYLE PATTERN- Many lifestyle factors such as cigarette smoking, illicit drug use,  alcohol and caffeine consumption, psychological stress, and  environmental and occupational exposure have substantial effects on fertility.  

RISKS ASSOCIATED WITH ADVANCED MATERNAL AGE (AMA)

 

Some of the major risks of Advanced maternal age include:-

  1. Chromosomal abnormalities and birth defects.
  2. Premature birth, still birth, and miscarriages.
  3. Low  birth weight.
  4. Labor complications and Caesarean delivery
  5. Multiple pregnancies  such as twins and triplets
  6. Preeclampsia ( High blood pressure in pregnancy)
  7. Gestational Diabetes.

 

WHEN TO SEEK ADVICE FROM MEDICAL PRACTITIONER

 

As no remedies are available to counteract the aging-related fertility decay , therefore different therapeutic approaches can be offered to women with advanced maternal age  such as IVF In vitro Fertilization.  Women with age 35 and older can undergo IVF procedure in order to achieve pregnancy. In IVF, mature eggs are retrieved from ovaries and fertilized by sperm artificially in a lab and then fertilized embryos transferred to a uterus. There are certain things which can be taken care during advanced maternal age pregnancy for healthy baby.

 

EFFECTIVE MEASURES TO MAINTAIN ADVANCED MATERNAL AGE PREGNANCY-

  1. Eating a balanced healthy diet can fill the gaps. Add more calcium, iron, vitamin D, folic acid and other essential nutrients in diet.
  2. Begin  taking a prenatal vitamin a few months before conception.
  3. Maintaining the right amount of weight can support baby’s health.
  4. Regular physical activity can easy the discomfort during pregnancy and boost energy and stamina.
  5. Avoid risky substances such as alcohol, drugs, tobacco and caffeine consumption. Also check with health care provider before taking any medications and supplements.

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