When it comes to IVF success, Frozen Embryo Transfer (FET) is often considered a better option than fresh embryo transfer for many patients. FET allows for better uterine lining preparation, reduced health risks like OHSS, and higher success rates in select groups such as women with PCOS or those undergoing preimplantation genetic testing (PGT). However, the best choice depends on your medical profile, fertility goals, and personal preferences.
Let’s dive deeper to understand whether frozen embryo transfer is truly better than a fresh transfer and how to make an informed choice.
What is Frozen Embryo Transfer (FET)?
In IVF (In Vitro Fertilisation), embryo transfer is the final step where an embryo is placed into the woman’s uterus. There are two main types of embryos:
- Fresh Embryo Transfer: The embryo is transferred into the uterus a few days (typically 3 to 5) after egg retrieval and fertilisation during the same IVF cycle.
- Frozen Embryo Transfer (FET): Embryos are frozen (cryopreserved) and transferred in a later menstrual cycle after thawing.
Over the past decade, advances in cryopreservation techniques, especially vitrification, have significantly increased the success and safety of frozen embryo transfers.
Success Rates: FET vs. Fresh Embryo Transfer
One of the top reasons patients and fertility specialists are leaning toward FET is its strong success rate in many cases.
- In different clinical observations, FET often leads to higher implantation and live birth rates, particularly in women under 35 and those with hormone-sensitive conditions like PCOS.
- Fresh embryo transfers may work better for women with a limited number of embryos or those who respond poorly to ovarian stimulation.
Key takeaway here is that FET gives your body time to recover from IVF medications, leading to a more natural hormonal environment that is better prepared for embryo implantation.
Hormonal Balance and Endometrial Receptivity
After ovarian stimulation, your hormone levels may be too high for optimal embryo implantation. In such cases, fresh transfer might not yield the best outcomes.
- With Frozen Embryo Transfer, your uterus has time to return to its natural hormonal state.
- This improves endometrial receptivity, making the uterine lining more suitable for embryo implantation.
Clinics now increasingly recommend a “freeze-all” strategy where all embryos are frozen and transferred in a future cycle to maximise pregnancy potential.
Is Frozen Embryo Transfer Safer?
Yes, for certain patients. FET significantly reduces the risk of Ovarian Hyperstimulation Syndrome (OHSS) — a potentially dangerous response to fertility drugs. Fresh transfers done during the same cycle as ovarian stimulation may elevate this risk, especially in women with high AMH levels or PCOS.
FET is also considered safer for both mother and baby, with some studies showing:
- Lower risks of preterm birth
- Better birth weights
- Reduced rates of placental complications
However, other research suggests a slightly higher chance of hypertensive disorders in frozen embryo pregnancies. Therefore, individualised care is important.
Advantage for Genetic Testing (PGT)
When you opt for Preimplantation Genetic Testing (PGT), FET becomes almost a necessity. Embryos need to be biopsied and tested for genetic abnormalities, and the results take time.
- Frozen embryos give you time for this testing process without rushing into a fresh transfer.
- This improves outcomes by ensuring only chromosomally normal embryos are implanted.
For older women or couples with a history of genetic issues, FET with PGT improves pregnancy rates and reduces miscarriage risks.
Emotional and Psychological Considerations
While both procedures involve emotional highs and lows, FET provides breathing space for patients between stimulation and implantation. This often allows time to:
- Mentally and physically recover.
- Make data-backed decisions based on embryo quality.
- Avoid the overwhelm of a tightly packed IVF schedule.
Some patients report that they feel more relaxed and in control with frozen embryo cycles.
Cost Comparison: Frozen vs. Fresh Transfers
While Frozen Embryo Transfer may cost more upfront (due to freezing, storage, and thawing), it can be more cost-effective in the long run.
- Higher success rates per cycle mean fewer IVF cycles are needed.
- Reduced risk of complications like OHSS saves money on medical interventions.
A rough cost comparison:
- Fresh embryo transfer: ₹75K to ₹1.2L per cycle
- Frozen embryo transfer: ₹1L to ₹1.5L per cycle (includes freezing and storage for 6–12 months).
Global Trends and Medical Recommendations
Around the world, the shift toward Frozen Embryo Transfers is increasing.
- In the US and Europe, over 70% of transfers are now frozen.
- Leading fertility clinics in India are also seeing more patients opting for FET due to better planning and improved outcomes.
Medical associations like ASRM (American Society for Reproductive Medicine) acknowledge FET as equally effective, if not superior, in many cases.
Are There Any Downsides to Frozen Embryo Transfer?
Despite its benefits, FET may not be ideal for every patient. Potential downsides include:
- Delay in the transfer process (you may wait 1–2 months after retrieval).
- Risk of embryo loss during thawing (though minimal with modern techniques).
- Slightly higher chances of pregnancy-induced hypertension.
Therefore, fresh embryo transfer may still be considered for:
- Women with low ovarian reserve and fewer embryos.
- Patients needing immediate implantation due to medical reasons.
Final Verdict: Which is Better?
Many believe that there is not such an all-in-one answer. But after looking at the advantages and positive acceptance of FET in certain medicals, the answer is clear.
Frozen embryo transfer (FET) is definitely better than fresh embryo transfer in terms of IVF success rate and birth rate. Why? Frozen Embryo Transfer (FET) offers:
- Better control of the uterine environment.
- Higher success rates (especially with PGT).
- Improved safety profile.
- Greater scheduling flexibility.
Always consult your fertility specialist to decide what works best for your unique reproductive health and IVF goals.
Ready for Frozen Embryo Transfer? Visit Vardaan IVF Clinic
If you’re planning IVF or still comparing your embryo transfer options, consult with an experienced fertility specialist in Jalandar. Whether you choose a fresh transfer or opt for a more controlled frozen embryo cycle, your treatment should be customised to maximise success while supporting your emotional and physical well-being.
Vardaan Hospital already has helped more than 30K couples with their pregnancy. We have over an 80% success rate in IVF and all the facilities available in the hospital. Book your appointment now!
